Thrombocytopenia in pregnancy


Description

Thrombocytopenia is known as having a platelet count of less than 150,000/µL of blood. It is common during normal pregnancy, complicates 10% of pregnancies, and is regarded as the second most common blood disorder after anemia. In 80% of the cases, it happens only during pregnancy and resolves spontaneously within the first two months after delivery.

Symptoms

Mild cases are usually asymptomatic, but symptoms may occur in more severe cases.

Nose bleeding
Bleeding gums
Abnormal uterine bleeding
Bloody urine
Gastrointestinal bleeding
Visit your Gynaecologist if you have any of these symptoms, he may refer you to a Hematologist If needed


Causes

There are many reasons which may be related to pregnancy or not.

Physiological changes during pregnancy
Preeclampsia
Acute fatty liver of pregnancy
Immunological disease
Some medications
Systemic lupus erythematosus disease
Viral infections
Bone marrow disorders
Liver disease

Diagnostics

A complete blood count examination is the main tool for thrombocytopenia diagnosis. The cause can be known through other laboratory tests such as:

Coagulation tests
Thyroid gland functions
Hepatitis B, and C screening
Liver function tests
H. Pylori test
Antibodies tests


Treatment

If there is no bleeding and the platelets count is more than 30,000/µL, there is no need to start medications until delivery.

If treatment is needed to be started during pregnancy, and the thrombocytopenia is caused by reasons not related to pregnancy, some medications can be used such as Prednisone, Prednisolone, and Immunoglobulin.

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