Myasthenia gravis is a complicated autoimmune condition. Antibodies attack the connections between your muscles and nerves. This results in muscle weakness and fatigue.
Because of the added weight and effort of pregnancy, myasthenia gravis may be of particular concern during pregnancy
Myasthenia gravis is characterized by weak muscles that exhibit indicators of weakness, ptosis, diplopia, breathing and swallowing problems, and weak limbs. The symptoms are typically at their worst within two years and are frequently made worse by emotional stress, infections, pregnancy, thyroid issues, and other illnesses.
Some women may experience a myasthenic crisis in which their breathing muscles are unable to function correctly, leading to respiratory collapse.
Book an appointment with your gynaecologist right away if you experience any of these symptoms. He might refer you to a neurologist for case further management.
The immune system attacks nerve and muscle cell connections as a result of genetics causes, environmental factors, and allergies.
Myasthenia gravis symptoms vary in severity; they worsen with exertion and improve with rest.
A physical exam.
Diagnostic testing, such as radioimmunoassay-based antibody titration (anti-AChR and anti-MuSK), nerve testing, and edrophonium injection.
Additional testing, such as computed tomography (CT), MRI, and ultrasound.
The neurologist can confirm the diagnosis thanks to the combination of test results.
Plasmapheresis: A safe and expensive procedure used in myasthenic crisis patients. Plasmapheresis is a highly effective treatment when combined with steroids.
Intravenous immunoglobulin: inhibits anti-AChR antibodies. Improvement is visible in 3-21 days and can last up to 3 months.
Thymectomy: eliminate an antigen source while decreasing an anti-AChR antibody source
Other Treatment Options, such as Diet and Activity, Postsurgical Care, and Postdelivery Care
Narcotics, Tranquilizers, Barbiturates, Inhalation anesthetics (i.e., halothane, trichloroethylene, ether), Magnesium and lithium salts, Penicillamine, Beta-adrenergic agents, Quinidine, Aminoglycoside antibiotics, Colistin, Neomycin, Tetracycline drugs, Lincomycin, Polymyxin, Quinacrine, Chloroquine are examples Pregnant women and female patients who may become pregnant should not be given rituximab, mycophenolate mofetil, methotrexate, or cyclophosphamide.
Individualized treatment plans and regular patient monitoring by a neurologist and gynaecologist throughout pregnancy are essential.
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