Lipid deposition, fibrosis, and calcification of the mitral valve support ring are all symptoms of the chronic condition known as mitral annular fibro-calcification (MAC). According to published studies, MAC varied between 8 and 14%.
In the elderly, mitral annular calcification is an increasing issue. It results in difficult-to-treat regurgitation and mitral stenosis.
The comorbidities that may be present in patients with mitral annular calcification (MAC) are numerous. Any of these concomitant disorders may physically manifest in MAC patients. The comorbidities that are most strongly linked to MAC include:
Stroke, atherosclerosis, chronic renal disease, mitral regurgitation, mitral stenosis, arrhythmias, atrial fibrillation, endocarditis, and aortic valve disease are just a few of the illnesses that might occur.
Book an appointment with your General Practice doctor or Diabetes and Endocrinology doctor who might refer you to a Cardiologist if you have history of the above-mentioned conditions, feel unwell or just wanted to get reassured.
ccording to reports, the mitral annulus' calcification accelerates when:
Advancing years, diseases that increase annular stress (such as mitral valve prolapse), systemic hypertension, hypercholesterolemia, diabetes mellitus, chronic renal failure with secondary hyperparathyroidism, and genetic anomalies of the fibrous skeleton (e.g., Marfan and Hurler syndromes).
Cardiovascular disease (CVD) and mitral annular calcification (MAC) are related, however, there is little proof that risk factor management affects MAC progression.
Imaging tests: Mitral annular calcification (MAC) on cardiac imaging is typically discovered incidentally. Transthoracic echocardiography identifies MAC as an echo-dense band or mass in the atrioventricular groove on the parasternal or apical views.
Histologic findings: Mitral annular calcification can never be diagnosed through biopsy (MAC).
Staging: The thickness of the mitral annular calcification (MAC) at the site of greatest breadth on M-mode echocardiography is used to categorize the severity of the condition.
A specific course of medical treatment is not necessary in the absence of asymptomatic mitral annular calcification (MAC). Concomitant cardiovascular risk factors should be managed well medically because MAC is linked to valvular disease, atherosclerosis, stroke, and other vascular disorders.
Surgical Care for MAC
Unless simultaneous mitral regurgitation or mitral stenosis correction is required, mitral annular calcification (MAC) does not require surgical therapy.
Medications
Antiplatelet medications: Prevent platelet aggregation by inhibiting cyclooxygenase and the process that follows.
Anticoagulants: They are said to be helpful because they inhibit the production of active clotting factors.
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